1. Apocalypse: (X-Men) Born in ancient Egypt, he was the world's first mutant. Conquering in the name of a twisted Darwinian creed, technology from the future makes this time-traveling techno-tyrant the ultimate supervillain.
2. Ra's Al Ghul: (Batman) Hailing from ancient Arabia, this alchemist discovered the secret to immortality and used his long life to build a global organization intent on halting ecological destruction at any cost. The ideal eco-terrorist.
3. Lex Luthor: (Superman) The quintessential mad scientist, businessman, and politician. A prolific genius, Luthor exists to destroy Superman, thereby showing humanity it doesn't need alien saviors to decide its fate.
4. Magneto: (X-Men) This Nazi concentration camp survivor fights to protect the mutant minority from institutionalized bigotry and slavery around the world.
5. The Emperor: (Star Wars) He created the greatest military force the galaxy had ever seen, and nearly succeeded in exterminating the Jedi. One bad galactic tyrant.
6. David Xanatos: (Gargoyles) Machiavellian businessman obsessed with obtaining immortality. A curiously thoughtful self-made man, this supervillain is perhaps the most complex.
7. Hush: (Batman) A childhood friend of Bruce Wayne's, Hush secretly coveted the death of his parents and the resultant wealth and freedom. When Wayne received this blessing instead of him, Hush swore vengeance.
8. Q: (Star Trek) The archetypal trickster god, this omnipotent intellect delights in manipulating the Enterprise crew.
9. Alpharius: (Warhammer) The youngest of his bio-engineered brothers, this planet-conquering general takes a resilience-based, ecological approach to combat strategy. Sometimes disappearing for weeks at a time simply to test the individuality and adaptability of his lieutenants, Alpharius is a man of secrets.
10. Mr. Sinister: (X-Men) Originally a human geneticist in Victorian England, Mr. Sinister made a Faustian bargain with a higher power resulting in the loss of his family. He now exists to destroy that which created him.
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