Is Nutrition Science Undergoing a Paradigm Shift?

Robert Lustig made a splash a while back with his claim that sugar is toxic. Since then the pushback against the popular account of the causes of the obesity epidemic has grown larger and more vocal. This fantastic video is a nice reformulation of the basic critique:

It's all very compelling, and Lustig has put greater emphasis this time around on the epistemology and methodology of his claims, which is great. His focus at the end on health policy and decisionmaking under uncertainty is a more controversial step, explicitly making the leap from scientist to advocate.